"in vitro inhibition of human erythrocyte acetylcholinesterase activity by zinc and mercury "
نویسندگان
چکیده
the effects of zinc and mercury on human erythrocyte acetylcholinestrase activity were studied. blood used in this study was obtained from 24 apparently healthy individuals and after hemolysation, was treted with 3 diferent concentrations of zinc and mercury. significant suppressions in acetylcholinestrase activity were recorded in treated samples by zinc and mercury. when compared to controls the remaining activity was found to be 53% with the highest concen.tration of zinc (2.1 mg/dl, p
منابع مشابه
INHIBITION OF HUMAN ERYTHROCYTE GLUCOSE 6-PHOSPHATE DEHYDROGENASE ACTIVITY BY DEHYDROEPIANDROSTERONE AND RELATED STEROIDS.
The inhibitory effects of several steroids on G6PD activity using intact erythrocytes are reported. Incubation of whole blood with dehydroepiandrosterone (DHEA) resulted in 42% and 12% inhibition in the enzyme activity in the presence and absence of oxygen, respectively. Addition of epinephrine and/or aminophylline into the incubation medium caused further enzyme inhibition suggesting a po...
متن کاملin vitro inhibition of acetylcholinesterase activity in human red blood cells by cadmium and lead
the effects of cadmium and lead on human erythrocyte acetylcholinesterase activity were studied. blood used in this study was obtained from 24 healthy individuals, then after hemolysation, treated with 3 various concentrations of cadmium and lead. a strong inhibition of acetylcholinesterase was noted in treated samples by cadmium and lead. the remaining activity in the case of lead, the remaini...
متن کاملInhibition of Human Erythrocyte Glucose 6-Phosphate Dehydrogenase by Cadmium, Nickel and Aluminium
متن کامل
inhibition of human erythrocyte glucose 6-phosphate dehydrogenase activity by dehydroepiandrosterone and related steroids.
the inhibitory effects of several steroids on g6pd activity using intact erythrocytes are reported. incubation of whole blood with dehydroepiandrosterone (dhea) resulted in 42% and 12% inhibition in the enzyme activity in the presence and absence of oxygen, respectively. addition of epinephrine and/or aminophylline into the incubation medium caused further enzyme inhibition suggesting a possibl...
متن کاملErythrocyte Acetylcholinesterase-Inhibitory Activity of Porphyrin Compounds
Acetylcholinesterase (AChE) inhibition is important because of its health-related implications. Three porphyrin derivatives, Tetraphenylporphinesulfonate (TPPS), 5, 10, 15, 20-Tetrakis (4sulfonatophenyl) porphyrinato Iron (III) Chloride (FeTPPS) and 5, 10, 15, 20-Tetrakis (4-sulfonatophenyl) porphyrinato Iron (III) nitrosyl Chloride (FeNOTPPS), were tested by Molecular Docking as inhibitors of ...
متن کاملHuman Erythrocyte Acetylcholinesterase in Health and Disease.
The biochemical properties of erythrocyte or human red blood cell (RBC) membrane acetylcholinesterase (AChE) and its applications on laboratory class and on research are reviewed. Evidence of the biochemical and the pathophysiological properties like the association between the RBC AChE enzyme activity and the clinical and biophysical parameters implicated in several diseases are overviewed, an...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
acta medica iranicaجلد ۳۸، شماره ۳، صفحات ۱۵۶-۱۵۹
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023